Decoded Brain Circuits Show How Mice Stabilize Memories During Learning
New research in mice identifies brain circuits that make memories more stable during learning.
The study, published in Science, shows that activity in signaling pathways connecting two brain regions, the entorhinal cortex and the CA3 region of the hippocampus, helps mice form stable neural maps of places.
Cortical glutamatergic and GABAergic inputs support learning-driven hippocampal stability.
The study builds on data from previous studies that demonstrated the importance of the entorhinal/hippocampal circuit for memory formation and recalling memories by completing patterns from partial cues.
Author's summary: Brain circuits stabilize memories in mice during learning.
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